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Pediatric Oncology Branch Home > Clinical Programs > Hematologic Diseases > Clinical Trials

Headline Title

Hematologic Diseases

Clinical Trials

Leukemia and Lymphoma

Protocol Number	Long Title	Study Status	PI	Website	Section
08C0051 Pilot	A Pilot Trial of WT1 Peptide-Loaded Allogeneic Dendritic Cell Vaccine and Donor Lymphocyte Infusion for WT1-Expressing Hematologic Malignancies	Open to Accrual	Alan Wayne	Link	Hematologic/Blood Cancers
06C0233 Phase 1	A Phase I Study of the Raf Kinase and Receptor Tyrosine Kinase Inhibitor Sorafenib (BAY 43-9006, NSC# 724772 IND# 69896) in Children with Refractory Solid Tumors or Refractory Leukemias	Open to Accrual	Brigitte Widemann	Link	Pharmacology & Experimental Therapeutics, Sarcoma, Hematologic Diseases
08C0123 Phase 1	A Phase 1, Multi-Center, Dose Escalation Study of CAT-8015 in Children, Adolescents, and Young Adults with Refractory CD22+ Acute Lymphoblastic Leukemia (all) or Non-Hodgkin's Lymphoma (NHL)	Open to Accrual	Alan Wayne	Link	Pharmacology & Experimental Therapeutics, Hematologic Diseases
10C0119 Phase 1	A Phase 1 Study of Vorinostat and Bortezomib in Children with Refractory or Recurrent Solid Tumors, Including CNS Tumors and Lymphomas	Open to Accrual	Brigitte Widemann		Pharmacology & Experimental Therapeutics, Hematologic Diseases, Sarcoma, NeuroOncology
04C0173 Phase 2	Phase II Study of UCN-01 in Relapsed or Refractory Systemic Anaplastic Large Cell and Mature T-Cell Lymphomas	Open to Accrual	Wyndham Wilson	Link	Hematologic Diseases
01C0030 Other	Short-Course EPOCH - Rituximab in Untreated CD-20+ HIV-Associated Lymphomas	Open to Accrual	Wyndham Wilson	Link	Hematologic Diseases
04C0102 Other	Hematologic Malignancy Biology Study	Open to Accrual	Alan Wayne		Hematologic Diseases
10C0019 Other	Development and validation of a symptom scale for children with chronic graft-versus-host disease	Open to Accrual	Lori Wiener		Hematologic Diseases, Psychosomatic
11C0073	A Phase I Study of NK Cell Infusion Following Allogeneic Peripheral Blood Stem Cell Transplantation from Related or Matched Unrelated Donors in Pediatric Patients with Solid Tumors and Leukemias	Open to Accrual	Kristin Baird	Link	Sarcoma

 

Coming Trials:

1. A Phase I Study of NK Cell Infusion Following Allogeneic Peripheral Blood Stem Cell Transplantation from Related or Matched Unrelated Donors in Pediatric Patients with Solid Tumors and Leukemias. 
2. R049 COG Trial

Currently Closed to Accrual:

1. 01-C-0125   Pilot Study of Non-myeloablative,
   HLA-matched Allogeneic Stem Cell

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