Multiple endocrine neoplasia (MEN) types 2A and 2B are rare genetic diseases, which lead to the development of medullary thyroid cancer, usually in childhood. Surgery is the only standard treatment. Patients with medullary thyroid cancer can be cured only by thyroidectomy, but only when it is performed at a time when the tumor is confined to the thyroid gland. Traditional chemotherapy is not effective in this cancer. The PET Section has developed a clinical trial with the targeted agent vandetanib for children and young adults with medullary thyroid carcinoma and is currently ongoing.
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