All Clinical Trial Listings
Please click the links below to go to each Clinical Trial Listing on this page:
| Protocol Number | Title | Study Status | PI | Website | Section |
|---|---|---|---|---|---|
| Pilot | |||||
| 01C0030 | Short-Course EPOCH - Rituximab in Untreated CD-20+ HIV-Associated Lymphomas | Open to Accrual | Wyndham Wilson | Link | Hematologic Diseases |
| 07C0086 | Pilot Study of Educational Interventions in Pediatric Hematopoietic Stem Cell Donors to Increase Knowledge of Donation and Transplantation Procedures | Open to Accrual | Lori Wiener | GVHD, Psychosocial, Transplant | |
| 07C0206 | A Pilot Study of Tumor Vaccination and RHIL-7 Following Standard Multimodality Therapy in Patients with High Risk Pediatric Solid Tumors | Open to Accrual | Crystal Mackall | Link | Sarcoma |
| 08C0051 | A Pilot Trial of WT1 Peptide-Loaded Allogeneic Dendritic Cell Vaccine and Donor Lymphocyte Infusion for WT1-Expressing Hematologic Malignancies | Open to Accrual | Alan Wayne | Link | Hematologic/Blood Cancers |
| 08C0148 | A Pilot Study of Imatinib Mesylate in Children and Adults with Sclerotic Skin Changes of Chronic Graft-Versus-Host Disease | Open to Accrual | Edward Cowen | Link | |
| 10C0030 | A Study of Bevacizumab, a Humanized Monoclonal Antibody Against Vascular Endothelial Growth Factor (VEGF), in Combination with Chemotherapy for Treatment of Osteosarcoma | Open to Accrual | Su Young Kim | Sarcoma | |
| 10C0105 | A Pilot Study Evaluating 18F-L-Thymidine (FLT) PET Imaging in Children with Gliomas | Open to Accrual | Kathy Warren | NeuroOncology | |
| 11C0113 | A Pilot Study of Genetically Engineered NY-ESO-1 Specific (c259) T cells in HLA-A2+ Patients with Synovial Sarcoma |
Open to Accrual | Crystall Mackall | Sarcoma | |
| Phase I | |||||
| Protocol Number | Title | Study Status | PI | Website | Section |
| 06C0233 | A Phase I Study of the Raf Kinase and Receptor Tyrosine Kinase Inhibitor Sorafenib (BAY 43-9006, NSC# 724772 IND# 69896) in Children with Refractory Solid Tumors or Refractory Leukemias | Open to Accrual | Brigitte Widemann | Link | Pharmacology & Experimental Therapeutics, Sarcoma, Hematologic Diseases |
| 08C0007 | A Phase I Study of Ipilimumab (Anti-CTLA4) in Children, Adolescents, and Young Adults with Treatment Refractory Cancer | Open to Accrual | Crystal Mackall | Link | Pharmacology & Experimental Therapeutics, Sarcoma |
| 08C0123 | A Phase 1, Multi-Center, Dose Escalation Study of CAT-8015 in Children, Adolescents, and Young Adults with Refractory CD22+ Acute Lymphoblastic Leukemia (all) or Non-Hodgkin's Lymphoma (NHL) | Open to Accrual | Alan Wayne | Link | Pharmacology & Experimental Therapeutics, Hematologic Diseases |
| 08C0180 | Phase I Trial of the Raf Kinase and Receptor Tyrosine Kinase Inhibitor Sorafenib (BAY 43-9006, Nexavar) in Children and Young Adults with Neurofibromas Type 1 and Inoperable Plexiform Neurofibromas | Open to Accrual | Brigitte Widemann | Link | Pharmacology & Experimental Therapeutics, Neurofibromas |
| 09C0243 | A Phase I Study of ABT-888, an Oral Inhibitor of Poly(ADP-ribose)Polymerase and Temozolomide in Children with Recurrent/Refractory CNS Tumors | Clinical Hold | Kathy Warren | Link | NeuroOncology, Pharmacology & Experimental Therapeutics |
| 10C0119 | A Phase 1 Study of Vorinostat and Bortezomib in Children with Refractory or Recurrent Solid Tumors, Including CNS Tumors and Lymphomas | Open to Accrual | Brigitte Widemann | Pharmacology & Experimental Therapeutics, Hematologic Diseases, Sarcoma, NeuroOncology | |
| 10C0120 | A Phase I Study of Pazopanib as a Single Agent for Children with Refractory Solid Tumors | Open to Accrual | Brigitte Widemann | Pharmacology & Experimental Therapeutics, Sarcoma | |
| 11C0047 | Phase I Trial and Pharmacokinetic Study of the Oral Platinum Analog Satraplatin in Children and Young Adults With Refractory Solid Tumors Including Brain Tumors | Open to Accrual | Brigitte Widemann | Link | Pharmacology & Experimental Therapeutics, Sarcoma, NeuroOncology |
| 10C0219 | A Phase I Trial of Lenalidomide and Radiotherapy in Children with Diffuse Intrinsic Pontine Gliomas and High-grade Gliomas |
Open to Accrual | Kathy Warren | Link | NeuroOncology |
| Phase 1 & 2 | |||||
| Protocol Number | Title | Study Status | PI | Website | Section |
| 07C0189 | Phase I/II Trial of Vandetanib (ZD6474, ZACTIMA) in Children and Adolescents with Hereditary Medullary Thyroid Carcinoma | Open to Accrual | Brigitte Widemann | Link | Pharmacology & Experimental Therapeutics, Medullary Thyroid Carcinoma |
| Phase 2 | |||||
| Protocol Number | Title | Study Status | PI | Website | Section |
| 04C0173 | Phase II Study of UCN-01 in Relapsed or Refractory Systemic Anaplastic Large Cell and Mature T-Cell Lymphomas | Open to Accrual | Wyndham Wilson | Link | Hematologic Diseases |
| 06C0043 | Phase II Trial of Chemotherapy in Sporadic and Neurofibromas Type 1 Associated High Grade Malignant Peripheral Nerve Sheath Tumors | Open to Accrual | Brigitte Widemann | Link | Neurofibromatosis, Solid Tumors |
| 08C0080 | SARC Global Collaboration*: A Phase II Trial of R1507, a Recombinant Human Monoclonal Antibody to the Insulin-Like Growth Factor-1 Receptor for the treatment of Patients with Recurrent or Refractory Ewing’s Sarcoma, Osteosarcoma, Synovial Sarcoma, Rhabdom | Open to Accrual | Lee Helman | Link | Solid Tumors |
| 08C0096 | A Phase II Study of the mTOR Inhibitor Sirolimus in Neurofibromas Type 1 Related Plexiform Neurofibromas | Open to Accrual | Brigitte Widemann | Link | Neurofibromatosis |
| 08C0130 | A Phase II Trial of Peginterferon alfa-2b (Pegintron) for Neurofibromatosis Type I Related Unresectable, Symptomatic or Life-Threatening Plexiform Neurofibromas | Open to Accrual | Brigitte Widemann | Link | Neurofibromatosis |
| 09C0104 | A Randomized, Double-Blinded, Placebo-Controlled, Multi-Institutional, Phase II.5 Study of AZD0530, a Selective Src Kinase Inhibitor, In Patients with Recurrent Osteosarcoma Localized to the Lung | Open to Accrual | Su Young Kim | Link | Solid Tumors |
| 11C0115 | Phase 2 Study of Bevacizumab in Children and Adults with Neurofibromatosis Type 2 and Symptomatic Vestibular Schwannoma |
Open to Accrual | Brigitte Widemann | Neurofibromatosis
|
|
| Natural History | |||||
| Protocol Number | Title | Study Status | PI | Website | Section |
| 04C0275 | Targeted Oncolytic Virotherapy and Natural History Study of KSHV-Associated Multicentric Castleman's Disease with Laboratory and Clinical Correlates of Disease Activity | Open to Accrual | Robert Yarchoan | Link | |
| 08C0079 | Natural History Study and Longitudinal Assessment of Children, Adolescents, and Adults with Neurofibromas Type 1 | Open to Accrual | Brigitte Widemann | Link | Neurofibromas |
| Screening | |||||
| Protocol Number | Title | Study Status | PI | Website | Section |
| 01C0157 | Eligibility Screening and Tissue Procurement for the National Cancer Institute (NCI), Pediatric Oncology Branch (POB) Clinical Research Protocols | Open to Accrual | Crystal Mackall | Link | All |
| Other | |||||
| Protocol Number | Title | Study Status | PI | Website | Section |
| 06C0233 | Psychological Benefits of a Normalized Camping Experience for Children with Cancer | Open to Accrual | Stephen Chanock | Psychosocial | |
| 98C0037 | Treatment of Children with Cancer | Open to Accrual | Crystal Mackall | All | |
| 02C0313 | CANCER RISK IN XERODERMA PIGMENTOSUM HETEROZYGOTES | Open to Accrual | Kenneth Kraemer | Link | |
| 03C0278 | A Comparative Study of Pediatric CNS Tumor Activity as Assessed by 18F-FDG PET Imaging and Proton Magnetic Resonance Spectroscopic Imaging (1H-MRSI) | Open to Accrual | Kathy Warren | Link | NeuroOncology |
| 04C0102 | Hematologic Malignancy Biology Study | Open to Accrual | Alan Wayne | Hematologic Diseases | |
| 06C0219 | An Exploratory Study of Biologic and Pathophysiologic Effects of Radiation Therapy in Pediatric Patients with Central Nervous System Tumors | Open to Accrual | Kathy Warren | Link | NeuroOncology |
| 07C0085 | An Exploratory Study of the Use of Five Wishes as a Tool for Advanced Care Planning in Young Adults with Metastatic, Recurrent, or Progressive Cancer or HIV Infection | Open to Accrual | Lori Wiener | Psychosocial | |
| 07C0110 | Analysis of Stored Data Collected from Individuals Administered Neurobehavioral Assessments on IRB-approved Protocols | Open to Accrual | Rohan Hazra | ||
| 09C0054 | A Group Wide Biology and Banking Study for Phase II Studies of R1507 | Open to Accrual | Lee Helman | Sarcoma | |
| 09CN148 | Thalomid and Carboplatin for the Treatment of Pediatric Brain Stem Glioma | Closed to Accrual | Kathy Warren | NeuroOncology | |
| 10C0019 | Development and validation of a symptom scale for children with chronic graft-versus-host disease | Closed to accrual | Lori Wiener | Link | GVHD (and psychosocial) |
| 10C0086 | Comprehensive Omics Analysis of Pediatric Solid Tumors and Establishment of a Repository for Related Biological Studies | Open to Accrual | Javed Khan | Sarcoma, NeuroOncology | |
This Page Last Reviewed on
February 26, 2013
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